Heart is a muscular pump .But it contains more of non muscular cells than contractile cells.
The average human heart which weighs 300 -400 grams . Contrary to the popular perception heart is not purely a muscular organ. In fact myocytes constitutes only 30% of heart mass. Rest formed by
1.Fibroblasts
2.Endothelial cells
3.Purkinje cells
4.Interstitial cells
5.Collagen
6.Fibrous skeleton
7.Extracellualr matrix.
Why is this [...]
Archive for July 2nd, 2008
Heart is not a pure muscle : Lesser known facts
Posted in cardiology-Anatomy, tagged anatomy, cardiac failure, cardiology, collage, drsvenkatesan, fibroblasts, heart, LV mass, myocardium on July 2, 2008 | Leave a Comment »
How is LAD angina differnt from RCA angina ? Can we localise the “Angina related artery ” from the the type of chest pain ?
Posted in Cardiology - Clinical, Infrequently asked questions in cardiology (iFAQs), Tutorial in clinical cardiology, tagged angina, angiogram, cardiology, coronary, drsvenkatesan, Heberdens, LAD, nstemi, RCA, STMI on July 2, 2008 | Leave a Comment »
How is LAD angina differnt from RCA angina ?
Can we localise the “Angina related artery “ from the the type of chest pain ?
Patients with stable angia many times have multivessel CAD. There has been some correlation with radiation of anginal pain and the culprit artery.If the angina spreads to jaw or neck it is [...]
How do you define apical impulse ?
Posted in Tutorial in clinical cardiology, tagged apical impulse, clinical cardiology, MD, palpation on July 2, 2008 | Leave a Comment »
Examinations in clinical cardiology
It is a brief early systolic outward thrust , followed by late systolic retraction felt by the palpating finger when the LV contracts and rotates , the LV apex and the adjacent interventricular septum hits against the chest wall. It is usually felt at the 5th left intercostal space just inside the [...]
What is the optimal dose of clopidogrel in ACS ?
Posted in cardiology -Therapeutics, tagged acs, aspirin, clopidogrel, nstemi, stemi on July 2, 2008 | Leave a Comment »
Aspirin confusion spreads to clopidogrel !
It all started with 75 mg clopidogrel in CURE study and others.
It went up to 150, 300, 600, and in some centres 900 mg.
No body knows how much clopidogrel optimally inhibits the platelet.
Aspirin had the same story three decades ago. It started from 40mg went up to 1200mg
and finally settled at 162mgs.
Why [...]
CAPTIM study – Ambulance crew better than interventional cardiologists ?
Posted in Cardiology -Interventional -PCI, tagged acs, captim, captim study, cardiology, drsvenkatesan, fibrinolysis, myocardial infarction, stemi, thrombolyis on July 2, 2008 | Leave a Comment »
The forgotten “Gem of a study” from lancet 2002 .
The fight between Primary angioplasty and thrombolysis was actually over in 2002 itself.But the cardiology community failed to , rather reluctant to accept the truth.A bolus of thrombolytic agent (TPA/RPA) can do almost the same if not better than a highly complex procedure called Primary PCI with [...]
Why the left atrium fails to hypertrophy even in severe mitral stenosis?
Posted in Uncategorized, tagged drsvenkatesan, hypertrophy, left atrium, mitral stenosis, stem cell on July 2, 2008 | Leave a Comment »
The left atrium always dilate to pressure overload.And it almost never hypertophies even whne the mean LA pressure raises to high levels. Why ?
1.The atrium basically has little muscle cells to hypertrophy.The left atrial thickness is only 2mm.
They are basically designed to passively fill the ventricles. But this is not always true physiologically.We
call it as [...]
Archives
Pages
Meta
-
