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Archive for April, 2009

Heparin was invented accidentally by a 26 year old  , Jay McLean, a  pre clinical  medical student  in 1916 .It was one of the greatest discovery  in  medicine .It helped us prevent blood from clotting.Frozen blood inside human circulatory system constituted one of important mechanisms  of  human  death.This ranged from acute myocardial infarction to cerebral [...]

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The importance of venous system
Cardiovascular system  consists  not only of  heart  but also   the blood delivery and retrieval   system namely  the arterial and venous circulation .As  the heart pumps , 6  liters   of blood  every minute  , it  has to   traverse the  entire venous circulation promptly ,  to  complete  the [...]

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Sick sinus syndrome  or sinus node dysfunction (SSS, SND ) is one of the common cause of  symptomatic bradycardia .The other cause for  pathological bradycardia is complete heart block.Together , these two entities share 99% of indications for permanentpacemaker implantation.
The sinus node can get affected in various diseases . The commonest cause for SND [...]

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LV dysfunction , perhaps  is  the most common  medical term used by  physicians  world over.But surprisingly , It is not easy to infer what they mean by it ! The term literally means left ventricle is not functioning all right .
LV dysfunction can be classified by many  ways.

Symptomatic vs Asymptomatic
Global vs  Regional
Reversible vs Permanent
Systolic vs  [...]

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The answer to this question  is not  easy  , as   one  would tend to believe . In fact this question , takes it for granted     revascularisation  will  improve the LV dysfunction in patients  with severe LV dysfunction.
The truth is , we  are not sure   about the mechanisms . How   revasculariastion  will have an [...]

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Coronary collateral circulation is the God’s gift to mankind.It has potential  benefits  ( and  of course real benefit !)  both during acute and chronic coronary syndrome.
Collaterals in CCS
The classical role of coronary collateral is in patients with chronic stable angina.It is quiet common to see patients with totally occluded  LAD or RCA with normal  LV [...]

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Diagnostic issues in cardiac failure : A  febrile pleural effusion in a patient with LV dysfunction .
Is it a transudate or exudate ?  How to confirm the pleural effusion is primarily cardiac failure related ?
When the classical protein criteria is inadequate or prone for errors
Try this more specific marker  within the pleural fluid
N-Terminal Brain naruretic [...]

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Radial access  for both diagnostic  coronary angiogram  and  PCI has been increasing steadily.Many centres have adopted an  exclusive radial approach. Newer ,  radial specific  hard ware  is  being produced.(Link) .It is surprising , radial approach has  gained momentum  primarily outside  USA (Europe , Japan, India ).The advantages of radial access is primarily , patient comfort, [...]

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Ectopic beats or premature depolarisations are the commonest  cardiac arrhythmia encountered . Human heart , is a  non stop  electro mechanical organ ,  and it is not surprising   ectopic beats are so common  and can literally originate  from every cell of heart. But , generally it   emanates  primarily from  the special conducting cells . At [...]

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Pacemaker rhythms  result in classical ECG with  LBBB morphology.It is a universally understood  fact that  RV pacing would  produce LBBB and LV pacing a  RBBB pattern in surface ECG.As with any other rules in medicine , it is not 100%  perfect .(May be 70%)
In the process of oversimplification of rules  we have forgotten a simple [...]

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